CX3CR1-GFP + macrophages capture antigen from the bronchial airways Our above findings regarding the positioning of CX3CR1-GFP + IMs and CD11c-YFP + DCs at some airway branchpoints may be significant, as antigen is likely to deposit on the walls of the airways at branchpoints where airflow changes directions.
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Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation.
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