Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.

The radiosensitizing effect of VE822, as quantitated by the dose modifying factor (DMF), was highly significant (P<0,0001) for ARID1A - cells but not for ARID1A competent cell lines ( Figure 1B ; Supplement Figure S1 and Table 1 ).

also in 132,142 other papers