Although it is unknown why the serum levels of adhesion molecules decrease in CRPS patients, DICAM, as an immunoglobulin superfamily cell adhesion molecule, showed a decreasing trend in the serum of CRPS patients.
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DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation.
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The sentences
TNF-α level showed an increasing trend in DICAM KO glial cells in stimulated conditions, but failed to show statistical significance.