Prognostic Relevance of <i>NPM1</i> and <i>FLT3</i> Mutations in Acute Myeloid Leukaemia, Longterm Follow-Up-A Single Center Experience.

Cancers (Basel) · 2022 · PMC9562865 · PMID 36230640

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borderline significanceno p-value reported

Particularly, the median survival in patients with both mutations ( FLT3 -ITDm/ NPM1 m) was 98 months [OS at 3y and 5y 60% +/− 8 (SE) and 56% +/− 8 (SE), respectively], worse than in the FLT3 -ITDwt/ NPM1 m, with a borderline significance ( p : 0.06) [in the ITDwt/ NPM1 m: the median survival was undefined, at 3y and 5y OS 80% +/− 4.8 (SE) and 71% +/− 6 (SE), respectively].

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