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Metformin Prevents or Delays the Development and Progression of Osteoarthritis: New Insight and Mechanism of Action.

Cells · 2022 · PMC9563728 · PMID 36230974

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a decreasing trendno p-value reported
Likewise, a lower rate of medial cartilage volume loss and a decreasing trend to undertake TKA over a 6-year period were observed in obese individuals with knee OA [ 48 ].

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