Characterization of Two Mouse <i>Chd7</i> Heterozygous Loss-of-Function Models Shows Dysgenesis of the Corpus Callosum and Previously Unreported Features of CHARGE Syndrome.

Int J Mol Sci · 2022 · PMC9569499 · PMID 36232804

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

marginal significancep = 0.07so close (0.05 < p ≤ 0.1)

Stress Induced hyperthermia showed that Chd7 +/Whi mutants had a lesser response (+1.42 °C ± 0.13 versus +1.84 °C ± 0.16 in mutants and controls, respectively) although reaching marginal significance ( p = 0.07).

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