Hepatocyte-Derived Prostaglandin E2-Modulated Macrophage M1-Type Polarization via mTOR-NPC1 Axis-Regulated Cholesterol Transport from Lysosomes to the Endoplasmic Reticulum in Hepatitis B Virus x Protein-Related Nonalcoholic Steatohepatitis.

Int J Mol Sci · 2022 · PMC9569602 · PMID 36232960

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

an increasing trendno p-value reported

Although there was no significant change in the overall liver/body-weight ratio, there was an increasing trend in the HBx + HFCD group and a significant decrease after intervention with ONO-AE3-208, suggesting that EP4 intervention could rescue HBx + HFCD-induced liver injury ( Figure 4 C).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.