While blocking BST2 on Bst2 S/+ NK cells significantly enhanced NK cell cytotoxicity, the same blocking on Bst2 S/- NK cells showed only a marginally insignificant enhancement of cytotoxicity ( Figure 4 D).
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BST2, a Novel Inhibitory Receptor, Is Involved in NK Cell Cytotoxicity through Its Cytoplasmic Tail Domain.
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