Thus, does TXA 2 signaling condition the metastatic niche to create a more nurturing environment? The effects of TP on cancer-associated fibroblasts have not been investigated; however, they are likely to be significant given the emerging role of these cells and TXA 2 signaling in tumor progression.
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The Role and Regulation of Thromboxane A<sub>2</sub> Signaling in Cancer-Trojan Horses and Misdirection.
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