Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages.

Consequently, only a nonsignificant trend towards higher CD8 + T-cell levels was seen in αCD40-treated Xcr1 wt/dtr mice, which was incapable of restricting B16F10 tumor growth ( Fig. 3F ).

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