Our findings are highly significant as they identify for the first time the tumor suppressive role of a small molecule inhibitor targeting FTO in solid tumors and establish a key pathway by which m 6 A modification mediates autophagic flux to modulate tumor progression.
← all excerpts
FTO-mediated autophagy promotes progression of clear cell renal cell carcinoma via regulating SIK2 mRNA stability.
1
—
—