Impacts of COVID-19 pandemic on preterm birth: a systematic review and meta-analysis.

Compared with the prepandemic period, we identified a significant decreased odds of preterm birth (PTB; <37 weeks' gestation; pooled odds ratio [OR; 95% confidence interval (CI)] = 0.96 [0.94, 0.98]; I 2 = 78.7%; 62 studies) and extremely PTB (<28 weeks' gestation; pooled OR [95% CI] = 0.92 [0.87, 0.97]; I 2 = 26.4%; 25 studies) during the pandemic, whereas there was only a borderline significant reduction in the odds of very PTB (<32 weeks' gestation; pooled OR [95% CI] = 0.93 [0.86, 1.01]; I 2 = 90.1%; 33 studies) between the two periods.

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There was a reduction in the odds of VPTB with a borderline significance (pooled OR [95% CI] = 0.93 [0.86, 1.01], I 2 = 90.1%, 33 studies; Fig. 3 ).

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