Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-Based Regimens.

Multivariate Cox regression analyses with a backwards selection criterion of p < 0.10 were also performed, including: menopausal status (premenopausal, postmenopausal), performance status (0, 1–2), estrogen receptor (ER)/progesterone receptor (PR) status (negative, positive), number of metastatic sites (1–2, 3), as well as each marker that was found to be a significant prognosticator or revealed a trend towards significance in the univariate analyses (p < 0.10).

also in 2,760 other papers

Also interesting was the marginally significant association of tumor VEGFR2 expression with improved PFS in patients with HER2-negative tumors.

also in 26,082 other papers