Barely Significant
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The effect of a low dose hydrogen-oxygen mixture inhalation in midlife/older adults with hypertension: A randomized, placebo-controlled trial.

Front Pharmacol · 2022 · PMC9585236 · PMID 36278221

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a decreasing trendno p-value reported
For ambulatory blood pressure, H 2 -O 2 intervention led to a decreasing trend in nighttime SBP and a significant decrease in nighttime DBP in comparison with baseline, while no changes were observed in the Air group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.