Significantly lower mean serum vitamin B12 and folic acid levels and a significantly higher frequency of serum iron deficiency in younger than in older atrophic glossitis patients.

In addition, 224 younger AG patients had significantly lower mean serum vitamin B12 and folic acid levels, a lower mean serum homocysteine level (marginal significance, P = 0.056), a significantly higher frequency of serum iron deficiency, and a significantly lower frequency of hyperhomocysteinemia than 840 older AG patients.

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20 , 21 In this study, although significantly lower mean serum vitamin B12 and folic acid levels and a higher frequency of serum folic acid deficiency in the younger AG patients than in the older AG patients were found, there were a marginally significant lower mean serum homocysteine level and a significantly lower frequency of hyperhomocysteinemia in the younger AG patients than in the older AG patients.

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