Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data.

Front Immunol · 2022 · PMC9592759 · PMID 36304471

Europe PMC DOI

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closest p · 1.0× alpha

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marginally significantP=0.05actually significant

We found that AC016876.1 showed marginally significant lower expression in Basal-like than Her2 patients with uninvolved lymph node (stage ;N0; P=0.05; Wilcoxon test; Figure S1H ).

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an overall trendno p-value reported

Comparative analysis between subtypes showed that the Basal-like subtype showed a distinct and unique expression pattern of genes and lncRNAs, with an overall trend towards low expression, the LumA and LumB subtypes had very similar expression patterns, with an overall trend towards high expression, and the expression pattern of genes and lncRNAs in Her2 subtype was not biased ( Figures 2C, D ).

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