Double-blind controlled dietary cross-over intervention with differentially fertilised intact lettuce leaves shows acute reduction in blood pressure in young adults, associated with faster uptake of nitrate than of phenolics.

Discussion Relevance for measuring the acute effect of lettuce consumption on BP in young healthy adults The present study found a small, marginally significant (P = 0.038) difference in BP between treatments during the period of maximum plasma/saliva NO 3 − concentrations in the HNLP treatment, and a more significant overall correlation between increased NO 3 − concentration in saliva and reduced systolic BP.

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