Localized Perivascular Therapeutic Approaches to Inhibit Venous Neointimal Hyperplasia in Arteriovenous Fistula Access for Hemodialysis Use.

Biomolecules · 2022 · PMC9599524 · PMID 36291576

Europe PMC DOI

hedged sentence

0.2800

closest p · 5.6× alpha

0.2800

boldest claim

The sentences

a nonsignificant trendp = 0.28not close (p > 0.1)

They hypothesized that BAPN administration could improve AVF patency and found that local delivery of BAPN in rat AVFs through an electrospun scaffold significantly decreased wall fibrosis (34.79 ± 3.83 versus 47.17 ± 8.65%; p = 0.03) and demonstrated a nonsignificant trend toward increased blood flow (34.03 ± 17.32 versus 24.80 ± 7.60 mL/min; p = 0.28) versus vehicle-loaded scaffolds at day 21 [ 58 ].

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