Trio-Drug Combination of Sodium Valproate, Baclofen and Thymoquinone Exhibits Synergistic Anticonvulsant Effects in Rats and Neuro-Protective Effects in HEK-293 Cells.

Curr Issues Mol Biol · 2022 · PMC9601194 · PMID 36286014

Europe PMC DOI

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extremely significantp < 0.001actually significant

Interestingly, the trio-drug combination of SVP (150 mg/kg) with BFN (5 mg/kg) and THQ (40 mg/kg) exhibited an extremely significant ( p < 0.001) anti-convulsant effect and synergism.

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