Interactions between Environmental Factors and Glutathione S-Transferase (GST) Genes with Respect to Detectable Blood Aluminum Concentrations in Jamaican Children.

Genes (Basel) · 2022 · PMC9601654 · PMID 36292793

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

Additionally, using a co-dominant model for GSTP1 , although the interaction between GSTP1 and GSTM1 was marginally significant (overall interaction p = 0.06), we found that among children with GSTM1 DD genotype, the odds of having a detectable BAlC in children with the GSTP1 Val/Val genotype was 0.20 times (or 1/5 times) that of those with the Ile/Ile genotype [OR (95% CI) = 0.20 (0.05, 0.82), p = 0.03].

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