Transcription Factors as Important Regulators of Changes in Behavior through Domestication of Gray Rats: Quantitative Data from RNA Sequencing.

These motifs showed a highly significant mutual similarity ( Figure 2 A, 0.01 < (log 10 ( p -value) < 1 × 10 −9 ), coinciding with the significant upregulation of the Ascl3 gene in the brain tissue samples of tame rats (P ADJ = 3.16 × 10 −4 and log 2 fold = 2.82, see Table 2 ).

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