Real world data on the prognostic significance of monocytopenia in myelodysplastic syndrome.

Patients with excess blasts (RAEB1/2) tended to have lower AMC (median 0.19 versus 0.32 for patients without excess blasts, p < 0.0001) and lower AMC were found in higher IPSS-R categories (very low, 0.37 × 109/L; low, 0.30 × 109/L; intermediate, 0.25 × 109/L; high, 0.16 × 109/L; very high, 0.20 × 109/L), while there was a highly significant difference in the AMC between higher risk (intermediate, high, very high) and lower risk (very low and low) MDS according to the IPSS-R (0.21 × 10 9 /L vs 0.33 × 10 9 /L, p < 0.0001).

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