Likewise, in the Flinders Sensitive Line (FSL) genetic rodent model of depression, an observed trend of decreased Gadd45b mRNA levels in these hypermethylated untreated rats is consistent with the demethylating function of Gadd45b in the adult brain ( Melas et al., 2012 ).
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The role of Gadd45b in neurologic and neuropsychiatric disorders: An overview.
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