A meta-analysis of 1761 CRC patients from 11 studies by Li et al [ 33 ] showed that HER2 overexpression was negatively correlated with OS, and similar results were obtained in different subgroups, although the authors admitted that this effect might not be significant.
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Long-term follow-up of HER2 overexpression in patients with rectal cancer after preoperative radiotherapy: A prospective cohort study.
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