Just as NIH projects such as “Most Wanted” identified abundant 16S rRNA amplicons that inspired a search for their genomes of origin ( Fodor et al., 2012 ), we believe a new project is needed to elucidate the phenotypes of strains with known genomes and highly significant associations with disease and health.
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Strain level and comprehensive microbiome analysis in inflammatory bowel disease <i>via</i> multi-technology meta-analysis identifies key bacterial influencers of disease.
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