A complete clinico-epidemiological and microbiological profile of candidemia cases in a tertiary-care hospital in Western India.

The ARTEMIS antifungal surveillance program also noted a decreasing trend in the isolation of C. albicans and an increase in NACs such as C. tropicalis (from 4.6% in 1997 to 7.5% in 2003) and C. parapsilosis (from 4.2% in 1997 to 7.3% in 2003). 18 Similar observations have been reported by studies across India. 3 , 5 , 16 , 19 – 21 The most probable reason for this shift seems to be excessive use of fluconazole, which has led to a survival advantage for resistant species like NAC.

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