24 , 25 Given that millions of outpatient antibiotic prescriptions are issued annually 26 and that the impact of those prescriptions toward the emergence of antibiotic resistance can persist for months, the contribution of outpatient antibiotic exposure to the overall burden of antibiotic resistance is likely to be significant and grossly underestimated.
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Antibiotic exposure and acquisition of antibiotic-resistant gram-negative bacteria among outpatients at a US Veterans Affairs medical center.
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