Barely Significant
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LBODP080 Mc3r Expression In Liver Tissue Is Partially Responsible For The Severity Of Murine MC3R Deficiency Associated Obesity

J Endocr Soc · 2022 · PMC9627641

Europe PMC
1
hedged sentence
0.1200
closest p · 2.4× alpha
0.1200
boldest claim

The sentences

a nonsignificant trendp=0.12not close (p > 0.1)
In the liver-specific Mc3r knockout mice, no significant total body composition changes and a nonsignificant trend towards worsened ITT AUCg (Alb-Cre+/+: n=8, 12795 ± 943; LoxP+/+, Alb-Cre+/+: n=8, 14893 ± 855 min*mg/dL, p=0.12) were observed; however, GTT AUCg was higher (Alb-Cre+/+: n=8, 19691 ± 1351; LoxP+/+, Alb-Cre+/+: n=9, 24450 ± 1657 min*mg/dL, p=0. 042), and there was an increase in liver weight (Alb-Cre+/+: n=8, 1. 025 ± 0. 09 g; LoxP+/+, Alb-Cre+/+: n=9, 1.44 ± 0. 09 g, p=0. 0007).

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