Alterations of DNA methylation and expression of genes related to thyroid hormone metabolism in colon epithelium of obese patients.

BMC Med Genomics · 2022 · PMC9628115 · PMID 36320063

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0610

boldest claim

The sentences

marginally significantP = 0.054so close (0.05 < p ≤ 0.1)

Nevertheless, for the adjusted analysis, the relation of THRB delta Ct with BMI and its relation to weight were marginally significant, ( P = 0.054 and P = 0.056, respectively).

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approximately significantP = 0.057so close (0.05 < p ≤ 0.1)

As for weight, the crude model showed a significant inverse relation ( P < 0.05) while, the adjusted model showed an approximately significant inverse relation with DIO3 methylation levels ( P = 0.057).

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approached near significanceP = 0.061so close (0.05 < p ≤ 0.1)

The adjusted model approached near significance ( P = 0.061).

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