Targeted RNA-sequencing analysis for fusion transcripts detection in tumor diagnostics: assessment of bioinformatic tools reliability in FFPE samples.

Explor Target Antitumor Ther · 2022 · PMC9630092 · PMID 36338518

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a decreasing trendno p-value reported

The detection of positive events in low reads-cases showed a decreasing trend in sensitivity ( Figure 3 ) suggesting a possible increase of false negative results in samples with low coverage.

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