A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization.

Blood Adv · 2022 · PMC9631632 · PMID 36069828

Europe PMC DOI

hedged sentence

0.0078

closest p · 0.2× alpha

0.0078

boldest claim

The sentences

highly significantP < .0078actually significant

We find a highly significant stabilization ( P < .0078; 2-tailed t test for 2 independent means, performed on F 1/2 ) of the D3 interface in the presence of ≈ 640 nM FVIII.

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