Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans.

Blood Adv · 2022 · PMC9631663 · PMID 35381074

Europe PMC DOI

hedged sentence

0.0002

closest p · 0.0× alpha

0.0002

boldest claim

The sentences

highly significantP = .0002actually significant

For confirmation, we applied IFNA16 rs28368163 as a tag SNV in a second ET validation cohort (n = 54) and reconfirmed a highly significant association ( P = .0002) and OR (4.51; CI, 1.92-10.56), nearly identical to that found in Cohort 1 ( Table 2 ).

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