Barely Significant
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Topical application of the plant extract SDTL-E in ovariectomized rats: A potential new approach for treating osteoporosis.

Front Med (Lausanne) · 2022 · PMC9631791 · PMID 36341259

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may not be significantno p-value reported
Some studies have shown that other osteoporosis drugs administered through oral gavage or injection in OVX-induced osteoporosis rats require longer time to restore bone strength than topical application of SDTL-E, and their efficacy may not be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.