The eye changes in IMPC were noted for lens morphology changes in both left and right eyes of at least one male and female, but without complete penetrance and just short of significance ( https://www.mousephenotype.org/data/charts?accession=MGI:96828&allele_accession_id=MGI:5494466&zygosity=heterozygote¶meter_stable_id=IMPC_EYE_016_001&pipeline_stable_id=JAX_001&procedure_stable_id=IMPC_EYE_001¶meter_stable_id=IMPC_EYE_016_001 ).
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Autosomal recessive LRP1-related syndrome featuring cardiopulmonary dysfunction, bone dysmorphology, and corneal clouding.
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