Barely Significant
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SPARE-Tau: A flortaucipir machine-learning derived early predictor of cognitive decline.

PLoS One · 2022 · PMC9632811 · PMID 36327215

Europe PMCDOI
1
hedged sentence
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

The sentences

almost reached significancep-value=0.059so close (0.05 < p ≤ 0.1)
In our analyses including all CU participants CSF p-tau predicted ADAS-Cog changes when using z-scored values and results almost reached significance for the cutoff analysis (p-value=0.059), We now include the following comment in the discussion; “One study has described inconsistent findings of CSF p-tau better predicting cognition in CU participants than tau PET(44).

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