Identification and validation of a poor clinical outcome subtype of primary prostate cancer with Midkine abundance.

It was discovered that treatment with MDKr impaired the expression of GZMB and PRF1 of tumor‐infiltrating CD8 + T cells (Figure 4B ) in tumors with low intratumoral MDK expression, and the IFN‐γ production showed a decrease with marginal significance (Figure 4C ).

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