Action mechanism of hypoglycemic principle 9-(R)-HODE isolated from cortex lycii based on a metabolomics approach.

In our study, kynurenine content displayed a decreasing trend in muscle, liver, kidney, plasma and faeces in the group treated with 9-(R)-HODE ( Figures 3A , 4A,B ), while the bacteria of the Ruminococcaceae and Lactobacillaceae families showed an upregulation and the Akkermansiaceae family presented a downregulation compared with the diabetic mice ( Figure 7B ).

also in 47,180 other papers