Finer resolution analysis of transcriptional programming during the active migration of chicken primordial germ cells.

Comput Struct Biotechnol J · 2022 · PMC9636429 · PMID 36382185

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an increasing trendno p-value reported

In our investigation, the proportion of G2/M cells was detected in an increasing trend from E2.5 to E8, along with the expression of migrating germ cell marker CXCR4 [6] and early/mitotic germ cell marker Pou5f3 [52] , indicating that the migrating PGCs are mitotically active. scRNA-seq is an innovative technique to identify the transcriptionally distinct clusters and heterogeneity of PGCs.

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