Barely Significant
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Estetrol Prevents Hot Flushes and Improves Quality of Life in Patients with Advanced Prostate Cancer Treated with Androgen Deprivation Therapy: The PCombi Study.

Eur Urol Open Sci · 2022 · PMC9637725 · PMID 36353657

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highly significantno p-value reported
Table 3 summarizes the endocrine results reported earlier [12] , demonstrating the highly significant and favorable endocrine antitumor effects of HDE4, even with this low number of patients, for PSA, free testosterone, and FSH, and for the bone parameters osteocalcin and CTX1.

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