Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group.

Front Immunol · 2022 · PMC9644109 · PMID 36389788

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a decreasing trendno p-value reported

Sirolimus combo pretreatment in vivo significantly attenuated the Co-mV induced IgM Sp and IgG Sp production, which correlated with a decreasing trend in the early levels (after day 1) of Co-mV induced Sp immunogen levels.

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