Screening of Adapalene Microsponges Fabrication Parameters with Insight on the In vitro Biological Effectiveness.

Drug Des Devel Ther · 2022 · PMC9644220 · PMID 36388080

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

exceedingly significantp < 0.0001actually significant

Two-way ANOVA revealed that there was an exceedingly significant difference between all treatments (p < 0.0001) and between the various used concentrations (p < 0.0001), as well as the interaction between treatment and concentrations (p = 0.005).

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highly significantno p-value reported

In a similar manner, the ADA-MS-EUD had a highly significant effect on cancerous cell viability of the M10 cell line with an IC 50 of 8.811 μg/mL (4.3, 2.24 folds reduction in IC 50 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.