Nonmalignant AR-positive prostate epithelial cells and cancer cells respond differently to androgen.

Endocr Relat Cancer · 2022 · PMC9644224 · PMID 36219867

Europe PMC DOI

hedged sentences

0.0614

closest p · 1.2× alpha

0.0614

boldest claim

The sentences

borderline significantP = 0.0614so close (0.05 < p ≤ 0.1)

In contrast to RWPE-1-AR, in LNCaP-pcDNA3.1 cells, only the androgen response pathway was borderline significant in GSEA (B–H adjusted P = 0.0614) when comparing 100 with 0 nM DHT (Supplementary Table 12).

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a small trendno p-value reported

Analysis of proportions of sub-G1 cells among the PI-stained cells from cell cycle analysis revealed a small trend of DHT-induced cell death in RWPE-1-AR cells, but the result was not statistically significant (Supplementary Fig. 5C).

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