Activation of Piezo1 contributes to matrix stiffness-induced angiogenesis in hepatocellular carcinoma.

Cancer Commun (Lond) · 2022 · PMC9648387 · PMID 36181398

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a decreasing trendno p-value reported

Among these differentially expressed angiogenesis‐related cytokines, most pro‐angiogenic factors in shPiezo1‐CM exhibited a decreasing trend in content.

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an increasing trendno p-value reported

The expression levels of Piezo1 and COL1 in HCC cells all showed an increasing trend with the increase of matrix stiffness (Figure 2A ).

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