However, in the post-hoc sensitivity analyses on a reduced sample of antipsychotic free UHR individuals we found a borderline significant association between a pattern of disturbed sleep-wake measures (lower TST, higher DSI) and lower FA in 7/48 WM regions explaining 11.38% of the covariance (omnibus test p = 0.033, LV3 p = 0.082) (see Supplementary Figure 4B for details).
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White matter microstructure and sleep-wake disturbances in individuals at ultra-high risk of psychosis.
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The sentences
Moreover, the group difference between UHR individuals and HCs on AWI and DSI were highly significant.