Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.

Nat Commun · 2022 · PMC9651905 · PMID 36369178

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highly significantno p-value reported

Moreover, this effect remained highly significant when instrumental variables were expanded to encompass all genome-wide significant non-HLA loci for serum IgA levels (inverse variance-weighted OR = 2.49 per SD of IgA level, 95%CI: 1.56–3.99, P < 0.001).

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