New, Eco-Friendly Method for Synthesis of 3-Chlorophenyl and 1,1'-Biphenyl Piperazinylhexyl Trazodone Analogues with Dual 5-HT<sub>1A</sub>/5-HT<sub>7</sub> Affinity and Its Antidepressant-like Activity.

Molecules · 2022 · PMC9658223 · PMID 36364104

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

The sentences

fairly significantno p-value reported

A fairly significant difference between the new compounds and trazodone is seen in the interaction with CYP P450.

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