After MLN2238 treatment for 24 h, the percentages of HuCCT-1 and CCLP-1 in the G2/M phase were significantly increased, whereas the cell population in the G0/G1 phase showed a decreasing trend ( Figures 4D,E ).
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MLN2238 exerts its anti-tumor effects <i>via</i> regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma.
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