Neuron-targeted Knockout of APE1 Forces Premature Cognitive Impairment and Synaptic Dysfunction in Adult Mice.

Aging Dis · 2022 · PMC9662274 · PMID 36465182

Europe PMC DOI

hedged sentence

0.3500

closest p · 7.0× alpha

0.3500

boldest claim

The sentences

a statistical trendp=0.35not close (p > 0.1)

We found that the discrimination index (i.e, the time spent exploring the novel object divided by the total time exploring both familiar and novel objects) displayed a statistical trend (p=0.35, Mann-Whitney U test, n=7/group) toward a decrease in the APE1 cKO mice compared to WT mice (data not shown).

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