Although PHB2 levels were not associated with the rs9679162 genotype (or were only borderline significant), they were markedly associated with GALNT14 expression (Fig. 6C ), which was correlated with postoperative outcomes (Fig. 6D and Tables S 2 – 4 ).
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GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells.
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