The human batokine EPDR1 regulates β-cell metabolism and function.

We found loci with genome-wide significant associations to EPDR1 expression in human islets (rs6965395 and rs1524054) and others that were borderline significant (rs4720265, rs3734952, rs10488617 and rs3213975 with nominal p-values = 2.5 × 10 −21 , 7.14 × 10 −21 , 4.5 × 10 −22 , 4.5 × 10 −22 , respectively).

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